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  • Tutorials on Screening

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  • Review Article2
  • Editorial1

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  • Dans, Antonio L2
  • Dans, Leonila F2
  • Silvestre, Maria Asuncion A2
  • Idzerda, Leanne1
  • Knottnerus, J André1
  • Tugwell, Peter1

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  • Journal of Clinical Epidemiology3

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  • Diagnostic test2
  • Health screening2
  • Screening test2
  • Confirmatory test1
  • Direct evidence1
  • Evidence summary1
  • Indirect evidence1
  • Preventive medicine1
  • Screening program1
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Tutorials on Screening

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  • Editorial

    New tutorial on screening

    Journal of Clinical Epidemiology
    Vol. 64Issue 3p229–230Published in issue: March, 2011
    • Peter Tugwell
    • J. André Knottnerus
    • Leanne Idzerda
    Cited in Scopus: 0
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      The Journal of Clinical Epidemiology recognizes the important role that tutorials play in the education of both senior scientists and young researchers. This month, we are publishing an excellent 2-part tutorial discussing the tradeoffs between the benefit and harm of health screening. Dans et al argue in the first of two tutorials that the potential benefits of health screening are easy to understand; however, there is a huge potential for physical and psychological harm that is not well recognized.
    • Tutorial

      Trade-off between benefit and harm is crucial in health screening recommendations. Part II: Evidence summaries

      Journal of Clinical Epidemiology
      Vol. 64Issue 3p240–249Published online: January 3, 2011
      • Maria Asuncion A. Silvestre
      • Leonila F. Dans
      • Antonio L. Dans
      Cited in Scopus: 11
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        Evidence on the effectiveness of health screening strategies may be direct (i.e., studies on screening vs. no screening) or indirect (i.e., studies that separately evaluate the screening test[s], the confirmatory test, or the treatment). Critical trade-offs in the balance between harm and benefit for many screening strategies mandate that advocates of health screening adhere to the ethical precepts of nonmaleficence, autonomy, confidentiality, and equity. In our first article, we pointed out five prerequisites to justifying a health screening program: (1) the burden of illness should be high, (2) the screening and confirmatory tests should be accurate, (3) early treatment (or prevention) must be more effective than late treatment, (4) the tests and the treatment(s) must be safe, and (5) the cost of the screening strategy must be commensurate with the potential benefit.
        Trade-off between benefit and harm is crucial in health screening recommendations. Part II: Evidence summaries
      • Tutorial

        Trade-off between benefit and harm is crucial in health screening recommendations. Part I: General principles

        Journal of Clinical Epidemiology
        Vol. 64Issue 3p231–239Published online: January 3, 2011
        • Leonila F. Dans
        • Maria Asuncion A. Silvestre
        • Antonio L. Dans
        Cited in Scopus: 23
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          Health screening is defined as the use of a test or a series of tests to detect unrecognized health risks or preclinical disease in apparently healthy populations to permit prevention and timely intervention. A health screening strategy consists of the sequence of a screening test, confirmatory test(s), and finally, treatment(s) for the condition detected. The potential benefits of health screening are easy to understand, but the huge potential for physical and psychological harm is less well recognized.
          Trade-off between benefit and harm is crucial in health screening recommendations. Part I: General principles
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