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  • AHRQ Series Part II: Methods Guide for Comparative Effectiveness - Guest Editor, Mark Helfand

    Finding evidence for comparing medical interventions: AHRQ and the Effective Health Care Program

    Journal of Clinical Epidemiology
    Vol. 64Issue 11p1168–1177Published online: June 20, 2011
    • Rose Relevo
    • Howard Balshem
    Cited in Scopus: 29
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      This article discusses search methodology to identify evidence for comparative effectiveness reviews (CERs) as practiced by the Effective Health Care program.
    • AHRQ Series Part II: Methods Guide for Comparative Effectiveness - Guest Editor, Mark Helfand

      Updating comparative effectiveness reviews: Current efforts in AHRQ's Effective Health Care Program

      Journal of Clinical Epidemiology
      Vol. 64Issue 11p1208–1215Published online: June 20, 2011
      • Alexander Tsertsvadze
      • Margaret Maglione
      • Roger Chou
      • Chantelle Garritty
      • Craig Coleman
      • Linda Lux
      • and others
      Cited in Scopus: 24
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        To review the current knowledge and efforts on updating systematic reviews (SRs) as applied to comparative effectiveness reviews (CERs).
      • AHRQ Series Part II: Methods Guide for Comparative Effectiveness - Guest Editor, Mark Helfand

        Conducting quantitative synthesis when comparing medical interventions: AHRQ and the Effective Health Care Program

        Journal of Clinical Epidemiology
        Vol. 64Issue 11p1187–1197Published online: April 8, 2011
        • Rongwei Fu
        • Gerald Gartlehner
        • Mark Grant
        • Tatyana Shamliyan
        • Art Sedrakyan
        • Timothy J. Wilt
        • and others
        Cited in Scopus: 320
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          This article is to establish recommendations for conducting quantitative synthesis, or meta-analysis, using study-level data in comparative effectiveness reviews (CERs) for the Evidence-based Practice Center (EPC) program of the Agency for Healthcare Research and Quality.
        • AHRQ Series Part II: Methods Guide for Comparative Effectiveness - Guest Editor, Mark Helfand

          Assessing applicability when comparing medical interventions: AHRQ and the Effective Health Care Program

          Journal of Clinical Epidemiology
          Vol. 64Issue 11p1198–1207Published online: April 4, 2011
          • David Atkins
          • Stephanie M. Chang
          • Gerald Gartlehner
          • David I. Buckley
          • Evelyn P. Whitlock
          • Elise Berliner
          • and others
          Cited in Scopus: 46
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            To describe a systematic approach for identifying, reporting, and synthesizing information to allow consistent and transparent consideration of the applicability of the evidence in a systematic review according to the Population, Intervention, Comparator, Outcome, Setting domains.
          • Review Article

            AHRQ Series Paper 4: Assessing harms when comparing medical interventions: AHRQ and the Effective Health-Care Program

            Journal of Clinical Epidemiology
            Vol. 63Issue 5p502–512Published online: September 29, 2008
            • Roger Chou
            • Naomi Aronson
            • David Atkins
            • Afisi S. Ismaila
            • Pasqualina Santaguida
            • David H. Smith
            • and others
            Cited in Scopus: 126
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              Comparative effectiveness reviews (CERs) are systematic reviews that evaluate evidence on alternative interventions to help clinicians, policy makers, and patients make informed treatment choices. Reviews should assess harms and benefits to provide balanced assessments of alternative interventions. Identifying important harms of treatment and quantifying the magnitude of any risks require CER authors to consider a broad range of data sources, including randomized controlled trials (RCTs) and observational studies.
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