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  • Original Article

    AHRQ Series Paper 5: Grading the strength of a body of evidence when comparing medical interventions—Agency for Healthcare Research and Quality and the Effective Health-Care Program

    Journal of Clinical Epidemiology
    Vol. 63Issue 5p513–523Published online: July 13, 2009
    • Douglas K. Owens
    • Kathleen N. Lohr
    • David Atkins
    • Jonathan R. Treadwell
    • James T. Reston
    • Eric B. Bass
    • and others
    Cited in Scopus: 353
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      To establish guidance on grading strength of evidence for the Evidence-based Practice Center (EPC) program of the U.S. Agency for Healthcare Research and Quality.
    • Discussion

      AHRQ Series Paper 1: Comparing medical interventions: AHRQ and the Effective Health-Care Program

      Journal of Clinical Epidemiology
      Vol. 63Issue 5p481–483Published online: October 2, 2008
      • Jean Slutsky
      • David Atkins
      • Stephanie Chang
      • Beth A. Collins Sharp
      Cited in Scopus: 42
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        In 2005, the Agency for Healthcare Research and Quality established the Effective Health Care (EHC) Program. The EHC Program aims to provide understandable and actionable information for patients, clinicians, and policy makers. The Evidence-based Practice Centers are one of the cornerstones of the EHC Program. Three key elements guide the EHC Program and thus, the conduct of Comparative Effectiveness Reviews by the EPC Program. Comparative Effectiveness Reviews introduce several specific challenges in addition to the familiar issues raised in a systematic review or meta-analysis of a single intervention.
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