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HIGHLIGHTS: What is new?
- •Development of best practice principles for prioritising questions for living guidelines.
- •Approaches for selection of questions for living mode using living criteria.
- •Practical prioritisation of questions via workflow planning and meaningful engagement with decision makers.
- •Revision of prioritisation levels throughout the living guideline lifecycle.
- •Consideration of when to retire a question from living mode and introduce new questions.
Abstract
Objective
This article is part of a series on methods for living guidelines, consolidating practical
experiences from developing living guidelines. It focuses on methods for identification,
selection, and prioritisation of clinical questions for a living approach to guideline
development.
Study design and setting
Members of the Australian Living Evidence Consortium (ALEC), the National Institute
of Health and Care Excellence (NICE) and the US Grading of Recommendations, Assessment,
Development and Evaluations (GRADE) Network, convened a working group. All members
have expertise and practical experience in the development of living guidelines. We
collated methods documents on prioritisation from each organisation’s living guidelines,
conducted interviews and held working group discussions. We consolidated these to
form best-practice principles, which were then edited and agreed on by the working
group members.
Results
We developed best-practice principles for 1) identification, 2) selection, and 3)
prioritisation, of questions for a living approach to guideline development. Several
different strategies for undertaking prioritising questions are explored.
Conclusion
The paper provides guidance for prioritising questions in living guidelines. Subsequent
papers in this series explore consumer involvement, search decisions, and methods
decisions, that are appropriate for questions with different priority levels.
Key words
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Article info
Publication history
Accepted:
December 21,
2022
Received in revised form:
December 18,
2022
Received:
May 5,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Elsevier Inc. All rights reserved.