Abstract
Background and Objectives
Methods
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Footnotes
Declaration of interest: Thomas Piggott: Member of the GRADE Working Group. Lorenzo Moja: Staff member of the Secretariat of the Expert Committee on the Selection and Use of Essential Medicines and an employee of the WHO, Geneva, Switzerland. Elie A. Akl: Member of the GRADE Working Group. John Lavis: Declared none. Graham Cooke: was the chair of the 2019 and 2021 EML Expert Committee. He is supported in part by the Imperial NIHR Biomedical Research Centre. Tamara Kredo: Member of the GRADE Working Group, Co-director of South African GRADE Network and member South African Essential Medicines List Committee. Hans Hogerzeil: Was secretary of the WHO Expert Committee from 1999 to 2007 and Director of WHO's Essential Medicines Department from 2003 to 2011. He declares unrelated consultancy work for WHO, the Access to Medicine Index, Health Action International, and Management Sciences for Health. Benedikt Huttner: Staff member of the Secretariat of the Expert Committee on the Selection and Use of Essential Medicines and an employee of the WHO, Geneva, Switzerland. Pablo Alonso-Coello: Member of the GRADE Working Group, Director Barcelona GRADE Center. Holger Schünemann: Member and co-chair of the GRADE Working Group, Director Cochrane Canada and McGRADE Centre.
Author Contributions: Thomas Piggott: Conceptualization; Data curation; Formal analysis; Investigation; Methodology; Project administration; Resources; Software; Validation; Visualization; Roles/Writing–original draft; Writing–review & editing. Lorenzo Moja: Conceptualization; Formal analysis; Investigation; Methodology; Validation; Roles/Writing–original draft; Writing–review & editing. Elie Akl: Formal analysis; Investigation; Methodology; Validation; Writing–review & editing. John Lavis: Formal analysis; Investigation; Methodology; Validation; Writing–review & editing. Graham Cooke: Investigation; Methodology; Validation; Writing–review & editing. Tamara Kredo: Investigation; Validation; Writing–review & editing. Hans Hogerzeil: Investigation; Validation; Writing–review & editing. Benedikt Huttner: Investigation; Validation; Writing–review & editing. Pablo Alonso-Coello: Investigation; Validation; Writing–review & editing. Holger J. Schünemann: Conceptualization; Formal analysis; Investigation; Methodology; Project administration; Resources; Supervision; Validation; Visualization; Roles/Writing–original draft; Writing–review & editing.