Advertisement

Update of the agency for healthcare research and quality guidance on using nonrandomized studies in evidence syntheses

  • Carlos A. Cuello-Garcia
    Correspondence
    Corresponding author: World Health Organization Collaborating Center for Infectious Diseases, Research Methods and Recommendations, Michael G. DeGroote Cochrane Canada & McMaster GRADE Centres; McMaster University, 1280 Main Street West, Hamilton, L8S 4L8, Ontario, Canada. Tel.: +1 905 525 9140; fax: +1 905 525 9140.
    Affiliations
    World Health Organization Collaborating Center for Infectious Diseases, Research Methods and Recommendations, Michael G. DeGroote Cochrane Canada & McMaster GRADE Centres, McMaster University, Hamilton, Ontario, Canada

    Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, L8S 4L8, Ontario, Canada
    Search for articles by this author
  • Holger J. Schünemann
    Affiliations
    World Health Organization Collaborating Center for Infectious Diseases, Research Methods and Recommendations, Michael G. DeGroote Cochrane Canada & McMaster GRADE Centres, McMaster University, Hamilton, Ontario, Canada

    Department of Health Research Methods, Evidence and Impact, McMaster University, 1280 Main Street West, Hamilton, L8S 4L8, Ontario, Canada

    Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, L8S 4L8, Ontario, Canada
    Search for articles by this author

      Abstract

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Clinical Epidemiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Schunemann H.J.
        • Santesso N.
        • Vist G.E.
        • Cuello C.
        • Lotfi T.
        • Flottorp S.
        • et al.
        Using GRADE in situations of emergencies and urgencies: certainty in evidence and recommendations matters during the COVID-19 pandemic, now more than ever and no matter what.
        J Clin Epidemiol. 2020; 127: 202-207
        • Norris S.
        • Atkins D.
        • Bruening W.
        • Fox S.
        • Johnson E.
        • Kane R.
        • et al.
        Selecting Observational Studies for Comparing Medical Interventions. Methods Guide for Effectiveness and Comparative Effectiveness Reviews.
        AHRQ, Rockville, MD2010
      1. Higgins J.P.T. Thomas J. Chandler J. Cumpston M. Li T. Page M.J. Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). John Wiley & Sons, Chichester, UK2022
        • Schunemann H.J.
        • Tugwell P.
        • Reeves B.C.
        • Akl E.A.
        • Santesso N.
        • Spencer F.A.
        • et al.
        Non-randomized studies as a source of complementary, sequential or replacement evidence for randomized controlled trials in systematic reviews on the effects of interventions.
        Res Synth Methods. 2013; 4: 49-62
        • Cuello-Garcia C.A.
        • Santesso N.
        • Morgan R.L.
        • Verbeek J.
        • Thayer K.
        • Ansari M.T.
        • et al.
        GRADE guidance 24 optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines.
        J Clin Epidemiol. 2021; 142: 200-208
        • Guyatt G.H.
        • Oxman A.D.
        • Vist G.
        • Kunz R.
        • Brozek J.
        • Alonso-Coello P.
        • et al.
        GRADE guidelines: 4. Rating the quality of evidence--study limitations (risk of bias).
        J Clin Epidemiol. 2011; 64: 407-415
        • Balshem H.
        • Helfand M.
        • Schunemann H.J.
        • Oxman A.D.
        • Kunz R.
        • Brozek J.
        • et al.
        GRADE guidelines: 3. Rating the quality of evidence.
        J Clin Epidemiol. 2011; 64: 401-406
        • Sterne J.A.
        • Hernan M.A.
        • Reeves B.C.
        • Savovic J.
        • Berkman N.D.
        • Viswanathan M.
        • et al.
        ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.
        BMJ. 2016; 355: i4919
        • Schunemann H.J.
        • Cuello C.
        • Akl E.A.
        • Mustafa R.A.
        • Meerpohl J.J.
        • Thayer K.
        • et al.
        GRADE Guidelines: 18. How ROBINS-I and other tools to assess risk of bias in non-randomized studies should be used to rate the certainty of a body of evidence.
        J Clin Epidemiol. 2018; 111: 105-114
        • Piggott T.
        • Morgan R.L.
        • Cuello-Garcia C.A.
        • Santesso N.
        • Mustafa R.A.
        • Meerpohl J.J.
        • et al.
        Grading of Recommendations Assessment, Development, and Evaluations (GRADE) notes: extremely serious, GRADE's terminology for rating down by three levels.
        J Clin Epidemiol. 2020; 120: 116-120

      Linked Article