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Review Article| Volume 152, P89-100, December 2022

Methods for developing and reporting living evidence synthesis

  • Josefina Bendersky
    Affiliations
    Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Catalunya, Spain

    Iberoamerican Cochrane Centre, Barcelona, Catalunya, Spain
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  • Ariadna Auladell-Rispau
    Affiliations
    Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Catalunya, Spain
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  • Gerard Urrútia
    Affiliations
    Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Catalunya, Spain

    Iberoamerican Cochrane Centre, Barcelona, Catalunya, Spain

    Universitat Autònoma de Barcelona, Barcelona, Catalunya, Spain
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  • María Ximena Rojas-Reyes
    Correspondence
    Corresponding author: Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau), Servei d'Epidemiologia Clínica i Salut Pública, Pavelló 18, Planta 0, Sant Antoni Ma Claret, 167, 08025 Barcelona, Spain. Tel.: +34 935537814; fax: +34 935537809.
    Affiliations
    Institut d’Investigació Biomèdica Sant Pau (IIB SANT PAU), Barcelona, Catalunya, Spain
    Search for articles by this author

      Abstract

      Background and Objectives

      Identify currently methodological aspects proposed for planning, conducting, and reporting living evidence (LE) synthesis. Develop a preliminary checklist of key LE synthesis elements.

      Methods

      A survey of methodological articles describing or analyzing methods for the design, conduction, or reporting of LE synthesis.

      Results

      Twelve methodological articles were identified and analyzed. Key elements were related to: i) definition of LE and characteristics of LE synthesis, ii) methods and tools for the living process, iii) new evidence integration (methods and considerations), iv) updates dissemination and publication, v) revisiting living parameters, and vi) protocol considerations for LE synthesis.

      Conclusion

      This survey displays basic methodological concepts that can drive the development of LE synthesis and identifies specific aspects with opportunities for development. The potential impact of the LE approach calls for a change in the current evidence synthesis updating processes to more open, collaborative, transparent, and efficient systems. LE approaches also challenge journal editors to shift toward more efficient processes for synthesis update dissemination, which minimizes the risks of reliability of published information.

      Keywords

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