The comprehensive diagnostic study: a new solution to old problems?

Published:December 02, 2013DOI:https://doi.org/10.1016/j.jclinepi.2013.09.007
      Diagnostic labeling is one of the key elements of clinical care. The diagnostic label is used to explain symptoms, initiate appropriate treatment, or provide prognostic information [
      • Knottnerus J.A.
      • van Weel C.
      • Muris J.W.
      Evaluation of diagnostic procedures.
      ]. Choosing the correct diagnostic label based on the available diagnostic information can be challenging. Especially in primary care, which is the first contact setting for an unselected patient population, the clinician is left to choose from a large list of diagnostic possibilities. A patient presenting with chest pain may suffer from an acute coronary syndrome, hyperventilation, esophagitis, muscle pain, or pulmonary embolism [
      • Knockaert D.C.
      • Buntinx F.
      • Stoens N.
      • Bruyninckx R.
      • Delooz H.
      Chest pain in the emergency department: the broad spectrum of causes.
      ].
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