Articles in this series have examined aspects of knowledge translation in detail, including various theoretical frameworks, types of interventions, implementation methods, issues related to measurement and evaluation of processes and outcomes of care, and the strengths and limitations of various study designs. This article draws upon what has come before and presents some “case studies” of high-quality and successful knowledge-to-action studies. The case studies (Kiefe et al. [
], examining the use of achievable benchmarks with audit and feedback to improve multiple processes of care for patients with diabetes; Kucher et al. [
- Kiefe C.I.
- Allison J.J.
- Williams O.D.
- Person S.D.
- Weaver M.T.
- Weissman N.W.
Improving quality improvement using achievable benchmarks for physician feedback: a randomized controlled trial.
JAMA. 2001; 285: 2871-2879
], examining decision support and prompts for improving care of hospitalized patients at risk of thromboembolism; and Gonzales et al. [
- Kucher N.
- Koo S.
- Quiroz R.
- Cooper J.M.
- Paterno M.D.
- Soukonnikov B.
- et al.
Electronic alerts to prevent venous thromboembolism among hospitalized patients.
N Engl J Med. 2005; 352: 969-977
], looking at a multifaceted intervention to decrease antibiotic prescribing for respiratory tract infections in the community) have in common that they addressed common and clinically important problems where the established evidence was already very strong and directed efforts at changing health professional patterns of practice.
- Gonzales R.
- Steiner J.F.
- Lum A.
- Barrett P.H.
Decreasing antibiotic use in ambulatory practice: impact of a multidimensional intervention on the treatment of uncomplicated acute bronchitis in adults.
JAMA. 1999; 281: 1512-1519
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- Improving quality improvement using achievable benchmarks for physician feedback: a randomized controlled trial.JAMA. 2001; 285: 2871-2879
- Electronic alerts to prevent venous thromboembolism among hospitalized patients.N Engl J Med. 2005; 352: 969-977
- Decreasing antibiotic use in ambulatory practice: impact of a multidimensional intervention on the treatment of uncomplicated acute bronchitis in adults.JAMA. 1999; 281: 1512-1519
- Association between hospital process performance and outcomes among patients with acute coronary syndromes.JAMA. 2006; 295: 1912-1920
- Improving antibiotic selection: a systematic review and quantitative analysis of quality improvement strategies.Med Care. 2006; 44: 617-628
- A qualitative study of increasing β-blocker use after myocardial infarction. Why do some hospitals succeed?.JAMA. 2001; 285: 2604-2611
- Practice based longitudinal qualitative interview study of computerized evidence based guideline in primary care.BMJ. 2003; 326: 314-322
- What is missing from descriptions of treatment in trials and reviews?.BMJ. 2008; 336: 1472-1474
- Publication guidelines for improvement studies in healthcare: evolution of the SQUIRE Project.Ann Intern Med. 2008; 149: 670-676
Published online: November 05, 2009
Accepted: August 16, 2009
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.