Abstract
Objective
This study examines the association of walking with mortality in persons with type
2 diabetes compared to those with normal glucose tolerance.
Study Design and Setting
This prospective study included community-dwelling adults from the Rancho Bernardo
Study aged 50–90 years in 1984–86 who had type 2 diabetes (n=347) or normal glucose tolerance (n=1,317). During the 10-year follow up, Cox proportional hazards modeling was used to
model time until death from all causes (n=538), coronary heart disease (CHD, n=143), other cardiovascular disease (non-CHD CVD, n=138), and other causes (n=257) while adjusting for multiple potential confounders.
Results
After adjusting for sex, age, smoking, body mass index, alcohol, exercise, history
of CHD, and other covariates, adults with diabetes who walked ≥1 mile per day were
half as likely to die from all causes combined (hazard ratio [HR]=0.54; 95% confidence interval [CI]: 0.33, 0.88), and less than one-fifth as likely
to die from non-CHD CVD (HR=0.19; 95% CI: 0.04, 0.86) compared to adults with diabetes who did not walk. Walking
was also protective among adults with normal glucose tolerance (HR=0.55; 95% CI: 0.32, 0.96).
Conclusion
Results suggest walking ≥1 mile per day may provide strong protection from all-cause
and non-CHD CVD mortality in older adults with diabetes.
Keywords
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Article info
Publication history
Published online: October 04, 2006
Accepted:
June 2,
2006
Identification
Copyright
© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
