We have previously examined mean arterial pressure (MAP) during coronary artery bypass
graft (CABG) surgery and showed that a high MAP during cardiopulmonary bypass (CPB)
of 80 mmHg resulted in significantly less morbidity and mortality when compared to
usual MAP (50–60 mmHg). The purpose of this new randomized trial among elective CABG
patients was to compare the efficacy of 2 strategies of MAP management during CPB:
80 mmHg (“Standard”) vs. a tailored MAP (“Custom”) determined by the patient's pre-bypass
MAP on major morbidity, mortality and quality of life.
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© 2003 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
