Abstract
This study investigate the relation between fish consumption, all-cause mortality,
and incidence of coronary heart disease (CHD). A total of 4,513 men and 3,984 women
aged 30–70 years, sampled randomly from the population in Copenhagen County, Denmark,
with initially examination in 1982–1992 was followed until 2000 for all-cause mortality
and until 1997 for first admission to hospital or death from CHD. Information on fish
consumption was obtained from a self-administered food-frequency questionnaire. Cox
proportional hazard analysis gave no evidence for an inverse association between fish
consumption and all-cause mortality or incident CHD after adjustment for confounders.
Among subjects with a priory-defined high risk of CHD there was a nonsignificant inverse
relation between fish intake and CHD morbidity (Hazard Ratio 1.28 (0.92–1.80) for
a consumption of fish of less than two times per month or less compared with once
a week), but there was relatively few cases in this subgroup. These data provides
no evidence for a protective effect of fish consumption on all-cause mortality or
incident CHD in the population as a whole, but it cannot be excluded that frequent
consumption of fish benefits those at high risk for CHD.
Keywords
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Article info
Publication history
Accepted:
November 7,
2002
Received in revised form:
July 23,
2002
Received:
October 12,
2001
Identification
Copyright
© 2003 Elsevier Science Inc. Published by Elsevier Inc. All rights reserved.
