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Letters to the editor| Volume 55, ISSUE 5, P531, May 2002

Quick estimation of threshold “number needed to treat”

        Recently, “number needed to treat” (NNT) has been increasingly reported as an index of treatment efficacy. Sinclair et al. proposed the idea and formula of threshold NNT [
        • Sinclair J.C.
        • Cook R.J.
        • Guyatt G.H.
        • Pauker S.G.
        • Cook D.J.
        When should an effective treatment be used? Derivation of the threshold number needed to treat and the minimum event rate for treatment.
        ] (NNTT) below which we can assume that NNT of the medical intervention is acceptable. In order to retain virtue of NNT, which enables us with ease to compare burden with benefit of treatment intuitively, we here show a simpler way to estimate NNTT.
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