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An epidemiologic study of the relationships of peptic ulcer disease in 50–54 year old, urban males with physical, health and smoking factors

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      Abstract

      402 subjects randomly selected from the total population of all males between the ages of 50–54 yr in one Prague city district were chosen for a comprehensive epidemiologic survey.
      The collected data included information on history of peptic ulcer disease (PUD) and 65 independent parameters grouped in 4 categories; (a) cardiovascular variables (b) respiratory tract and smoking habits, (c) ‘stress’ factors, and (d) physical and social status. Multiple regression analyses showed no associations between peptic ulcer and the variables in these four categories. When the population was analyzed by blood pressure quartiles significant positive correlations were noted for ECG signs of ventricular conduction defect, vital capacity, presence of bacteriuria, symptoms of headache, intermittent claudication, night dyspnea, nervousness, and history of hematuria. The possibility that subjects with high blood pressure and PUD have some unidentified factor in common is suggested.
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