Journal of Clinical Epidemiology
Volume 53, Issue 1 , Pages 47-55 , January 2000

Lessons learned from enrollment in the BEST study—A multicenter, randomized trial of group psychosocial support in metastatic breast cancer

  • Pamela J. Goodwin

      Affiliations

    • Department of Medicine, Division of Clinical Epidemiology, Clinical Epidemiology and Health Care Research Program, University of Toronto, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    • Corresponding Author InformationCorresponding author. Tel.: 416-586-8605; Fax: 416-586-8659.(P.J. Goodwin)
    • ,
  • Molyn Leszcz

      Affiliations

    • Department of Psychiatry, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Gail Quirt

      Affiliations

    • Mount Sinai Hospital, Toronto, Ontario, Canada
    • ,
  • Jan Koopmans

      Affiliations

    • Department of Oncology, Tom Baker Cancer Center, University of Calgary, Calgary, Alberta, Canada
    • ,
  • Andrew Arnold

      Affiliations

    • Department of Medicine, Hamilton Regional Cancer Center, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Elizabeth Dohan

      Affiliations

    • Department of Patient and Family Counseling, British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada
    • ,
  • Marilyn Hundleby

      Affiliations

    • Department of Psychology, Cross Cancer Institute, University of Alberta, Edmonton, Alberta, Canada
    • ,
  • Harvey Max Chochinov

      Affiliations

    • Department of Psychiatry, Department of Psychosocial Oncology, Manitoba Cancer Treatment and Research Foundation, University of Manitoba, Winnipeg, Manitoba, Canada
    • ,
  • Margaret Navarro

      Affiliations

    • Department of Psychiatry, Ottawa Regional Cancer Center, University of Ottawa, Ottawa, Ontario, Canada

Received 5 May 1998 ,Revised 7 June 1999 ,Accepted 13 July 1999.

References 

  1. Hunninghake DB, Darby CA, Probstfield JA. Recruitment experience in clinical trials (literature summary and annotated bibliography). Contr Clin Trials. 1987;8:6S–30S
  2. Mettlin C, Cummings KM, Walsh D. Risk factor and behavioural correlates of willingness to participate in cancer prevention trials. Nutr Cancer. 1985;7:189–198
  3. Goodwin PJ, Leszcz M, Koopmans J, Arnold A, Doll R, Chochinov H, et al. Randomized trial of group psychosocial support in metastatic breast cancer (the BEST Study). Cancer Treat Rev. 1996;22(suppl. A):91–96
  4. Spiegel D, Bloom JR, Kraemer HC, Gottheil E. Effect of psychological treatment on survival of patients with metastatic breast cancer. Lancet. 1989;ii:888–891
  5. Spiegel D. Can psychotherapy prolong cancer survival?. Psychosomatics. 1990;31:361–366
  6. Spiegel D, Spira J. Supportive-Expressive Group Therapy (A Treatment Manual of Psychosocial Intervention for Women with Recurrent Breast Cancer). Stanford, CA: Psychosocial Treatment Laboratory, Stanford University School of Medicine; 1991;
  7. Yalom ID. The Theory and Practice of Group Psychotherapy. New York: Basic Books; 1995;
  8. The Financial Post–Canadian Markets 1995 (69th Edition).
  9. Canadian Cancer Statistics 1995. Toronto, Canada: National Cancer Institute of Canada, 1995.
  10. Greer S, Moorey S, Bajuch JDR, Watson M, Robertson BM, Mason A, et al. Adjuvant psychological therapy for patients with cancer (a prospective randomized trial). Br Med J. 1992;304:675–680
  11. Ford MF, Jones M, Scannell T, Powles A, Coonibes RC, Evans C. Is group psychotherapy feasible for oncology outpatients, attenders selected on the basis of psychological morbidity?. Br J Cancer. 1990;62:624–626
  12. Honig SF. Treatment of metastatic disease. Hormonal therapy and chemotherapy. In:  Harris JR,  Lippman NE,  Morrow M,  Hellman S editor. Diseases of the Breast. Philadelphia: Lippincott-Raven Publishers; 1996;p. 669–734
  13. Fentiman IS, Julien J-P, van Dongen JA, van Geel B, Chetty U, Coibion M. Reasons for non-entry of patients with DCIS of the breast into a randomized trial (EORTC 10853). Eur J Cancer. 1991;27:450–452
  14. Martin JF, Henderson WG, Zacharski LR. Accrual of patients into a multihospital cancer clinical trial and its implications on planning future studies. Am J Clin Oncol. 1984;7:173–182
  15. Hunter CP, Frelica RW, Feldman AR, Bavier AR, Dunlap WH, Ford L, et al. Selection factors in clinical trials (results from the Community Clinical Oncology Program physicians patient log). Cancer Treat Rep. 1987;71:559–565
  16. Friedman MA, Cain DF. National Cancer Institute sponsored cooperative clinical trials. Cancer. 1990;65(suppl.):2376–2382
  17. Tate HC, Rawlinson JB. Randomized comparative studies in the treatment of cancer in the United Kingdom (room for improvement?). Lancet. 1979;ii:623–625
  18. Twelves CJ, Thomson CS, Young J, Gould A, for the Scottish Breast Cancer Focus Group and Scottish Cancer Therapy Networks . Entry into clinical trials in breast cancer (the importance of specialist teams). Eur J Cancer. 1998;34:1004–1007
  19. Yeomans-Kinney A, Vernon SW, Frankowski RF, Weber DM, Bitswa JM, Vogel VG. Factors related to enrollment in the Breast Cancer Prevention Trial at a comprehensive cancer centre during the first year of recruitment. Cancer. 1995;76:46–56
  20. Fallowfield LJ, Jenkins V, Brennan C, Sawtell M, Maynihan C, Souhami RL. Attitudes of patients to randomized clinical trials of cancer therapy. Eur J Cancer. 1998;34:1554–1559
  21. Rimer BK, Schildkraut JM, Lerman C, Lin TH, Andrain J for the High Risk Breast Cancer Consortium. Participation in a women's breast cancer risk counselling trial. Who participates? Who declines? Cancer 1996;77:2348–55.
  22. Cockburn J, Redman S, Kricker A. Should women take part in clinical trials in breast cancer?. Issues and solutions, J Clin Oncol. 1998;16:354–362
  23. Cox K, Avis M. Psychological aspects of participation in early anticancer drug trials. Reports of a pilot study, Cancer Nurs. 1996;19:177–186
  24. Tangrea J. Patients participation and compliance in cancer chemoprevention trials (issues and concerns). PSEBM. 1997;216:260–265
  25. DelGiudice ME, Leszcz M, Pritchard KI, Vincent L, Goodwin PJ. Attitudes of Canadian oncology practitioners toward psychological interventions in clinical and research settings in women with breast cancer. J Psychosoc Oncol. 1997;6:178–189
  26. Cunningham AJ, Edmonds CV, Jenkins GP, Pollack H, Lockwood GA, Warr DA. A randomized controlled trial of the effects of group psychological therapy on survival in women with metastatic breast cancer. Psycho-Oncology. 1998;7:508–517
  27. Fawzy FI, Fawzy NW, Hyun CS, Elashoff R, Guthrie D, Fahey JL, Morton DL. Malignant melanoma. Effects of an early structured psychiatric intervention, copying and affective state on recurrence and survival 6 years later. Arch Gen Psychol 1993;50:681–9.
  28. Spiegel D. Health care (psychosocial support for patients with breast cancer). Cancer. 1994;74:1453–1457

PII: S0895-4356(99)00148-1

Journal of Clinical Epidemiology
Volume 53, Issue 1 , Pages 47-55 , January 2000

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