Journal of Clinical Epidemiology
Volume 52, Issue 4 , Pages 337-346, April 1999

Rose Questionnaire Angina in Younger Men and Women:☆

Gender Differences in the Relationship to Cardiovascular Risk Factors and Other Reported Symptoms

  • Amanda Nicholson

      Affiliations

    • International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
    • ,
  • Ian R White

      Affiliations

    • International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
    • ,
  • Peter Macfarlane

      Affiliations

    • The Department of Medical Cardiology, Glasgow University, Glasgow, UK
    • ,
  • Eric Brunner

      Affiliations

    • International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK
    • Corresponding Author InformationAddress for correspondence: Eric Brunner, Department of Epidemiology & Public Health, University College London. 1-19 Torrington Place, LONDON WC1E 6BT, UK
    • ,
  • Michael Marmot

      Affiliations

    • International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London, UK

Accepted 12 January 1999.

Abstract 

Cross-sectional data from the Whitehall II study baseline were used to identify factors that may lead to the high levels of Rose angina reporting in women. 134 (4.0%) of 3350 women and 164 (2.4%) of 6830 men reported angina (P < 0.001). Women with Rose angina had a poorer cardiovascular risk profile (degree of obesity, serum cholesterol and apolipoprotein B, blood pressure) and more electrocardiogram abnormalities (ST and T changes) than women without angina, but the associations were generally weaker than in men. Women who reported many other physical symptoms had a high prevalence of Rose angina (9.7%). Adjustment for symptom reporting reduced the age-adjusted gender difference to odds ratio (OR) = 0.93 (95% confidence interval [CI]: 0.56–1.56) for subjects with no symptoms, and to OR = 1.42 (95% CI = 1.05–1.90) for subjects at the upper quartile of symptom score. Among women a high level of general symptom reporting was associated with General Health Questionnaire (GHQ) minor psychiatric morbidity (51.9% prevalence), but GHQ caseness does not appear to be a predictor of Rose angina (OR 1.22 [0.67–2.21]) in this group. Coronary artery disease risk is raised in women with Rose angina, and this remains true in groups with high levels of general symptom reporting.

Keywords:  Angina, sex differences, gender differences, Rose questionnaire, General Health Questionnaire

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

☆ Ian White is currently at the Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK.

PII: S0895-4356(99)00007-4

Journal of Clinical Epidemiology
Volume 52, Issue 4 , Pages 337-346, April 1999

Article Tools

* Image Usage & Resolution