Journal of Clinical Epidemiology
Volume 65, Issue 4 , Pages 404-412 , April 2012

Development and validation of clinical prediction models: Marginal differences between logistic regression, penalized maximum likelihood estimation, and genetic programming

  • Kristel J.M. Janssen

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31-30-2509380.
    • ,
  • Ivar Siccama

      Affiliations

    • Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    • ,
  • Yvonne Vergouwe

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands
    • ,
  • Hendrik Koffijberg

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands
    • ,
  • T.P.A. Debray

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands
    • ,
  • Maarten Keijzer

      Affiliations

    • Pegasystems Benelux, Amsterdam, The Netherlands
    • ,
  • Diederick E. Grobbee

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands
    • ,
  • Karel G.M. Moons

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P.O. Box 85500, 3508 AB Utrecht, The Netherlands

,Accepted 9 August 2011.

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 Disclosure: At the time of this study, Drs Keijzer and Siccama were affiliated with the company that developed the genetic programming software utilized in the study.

PII: S0895-4356(11)00270-8

doi: 10.1016/j.jclinepi.2011.08.011

Journal of Clinical Epidemiology
Volume 65, Issue 4 , Pages 404-412 , April 2012

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