A simple tool detected diabetes and prediabetes in rural Chinese

Abstract 

Objective

To develop and evaluate a simple tool, using data collected in a rural Chinese general practice, to identify those at high risk of Type 2 diabetes (T2DM) and prediabetes (PDM).

Study Design and Setting

A total of 2,261 rural Chinese participants without known diabetes were used to derive and validate the models of T2DM and T2DM plus PDM. Logistic regression and classification tree analysis were used to build models.

Results

The significant risk factors included in the logistic regression method were age, body mass index, waist/hip ratio (WHR), duration of hypertension, family history of diabetes, and history of hypertension for T2DM and T2DM plus PDM. In the classification tree analysis, WHR and duration of hypertension were the most important determining factors in the T2DM and T2DM plus PDM model. The sensitivity, specificity, positive predictive value, negative predictive value, and receiver operating characteristic area for detecting T2DM were 74.6%, 71.6%, 23.6%, 96.0%, and 0.731, respectively. For PDM plus T2DM, the results were 65.3%, 72.5%, 33.2%, 90.7%, and 0.689, respectively.

Conclusion

The classification tree model is a simple and accurate tool to identify those at high risk of T2DM and PDM. Central obesity strongly associates with T2DM in rural Chinese.

Keywords: Type 2 diabetes, Prediabetes, Risk factor, General practice, Screening, Classification tree analysis