Journal of Clinical Epidemiology
Volume 63, Issue 12 , Pages 1298-1304 , December 2010

Inconsistent trial assessments by the National Institute for Health and Clinical Excellence and IQWiG: standards for the performance and interpretation of subgroup analyses are needed

  • J. Hasford

      Affiliations

    • Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie, LMU München, Marchioninistr 15, 81377, München, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-89-70957480; fax: +49-89-70957482.
    • ,
  • P. Bramlage

      Affiliations

    • Institute for Cardiovascular Pharmacology and Epidemiology, 15831, Mahlow, Germany
    • ,
  • G. Koch

      Affiliations

    • Department of Biostatistics, University of North Carolina, Chapel Hill, NC 27599, USA
    • ,
  • W. Lehmacher

      Affiliations

    • Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, 50937 Köln, Germany
    • ,
  • K. Einhäupl

      Affiliations

    • Department of Neurology, Medical School, Charité, 10117 Berlin, Germany
    • ,
  • P.M. Rothwell

      Affiliations

    • Department of Clinical Neurology, Stroke Prevention Research Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK

,Accepted 12 October 2009.

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 Details of funding: none.

 Conflicts on Interest Disclosures: J.H., P.B., G.K., W.L., K.E., and P.M.R. declare to have received research support from a number of pharmaceutical companies including Sanofi-Aventis.

 Ethical approval: none required.

PII: S0895-4356(09)00365-5

doi: 10.1016/j.jclinepi.2009.10.009

Journal of Clinical Epidemiology
Volume 63, Issue 12 , Pages 1298-1304 , December 2010

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