Journal of Clinical Epidemiology
Volume 63, Issue 2 , Pages 117-125 , February 2010

The effect of study sponsorship on a systematically evaluated body of evidence of head-to-head trials was modest: secondary analysis of a systematic review

  • Gerald Gartlehner

      Affiliations

    • Department of Evidence-based Medicine and Clinical Epidemiology, Danube University, Krems, Austria
    • Corresponding Author InformationCorresponding author. Department of Evidence-based Medicine and Clinical Epidemiology, Danube University, Karl Dorrek-Straße 30, 3500 Krems, Austria. Tel.: +0043-2732-89327-2818; fax: +0043-2732-893-4810.
  • ,
  • Laura Morgan

      Affiliations

    • Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
  • ,
  • Patricia Thieda

      Affiliations

    • Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
  • ,
  • Anthony Fleg

      Affiliations

    • Department of Family and Community Medicine, University of New Mexico, Albuquerque, NM, USA

,Accepted 29 September 2008.

  • Image Result

    Relative-benefit meta-analysis (random effects) comparing response rates of selective serotonin reuptake inhibitors (SSRIs) when associated with the funding source with response rates of SSRIs when no

    Relative-benefit meta-analysis (random effects) comparing response rates of selective serotonin reuptake inhibitors (SSRIs) when associated with the funding source with response rates of SSRIs when not associated with the funding source.

  • Image Result
    Funnel plot of relative-benefit meta-analysis.

    Funnel plot of relative-benefit meta-analysis.

 Conflict of interest: None of the authors has any conflict of interest with respect to the topic of this manuscript. All authors had full access to the data of this study.

PII: S0895-4356(09)00231-5

doi: 10.1016/j.jclinepi.2008.09.019

Journal of Clinical Epidemiology
Volume 63, Issue 2 , Pages 117-125 , February 2010