Journal of Clinical Epidemiology
Volume 63, Issue 5 , Pages 566-574 , May 2010

BLISS index using WOMAC index detects between-group differences at low-intensity symptom states in osteoarthritis

  • Nicholas Bellamy

      Affiliations

    • Centre of National Research on Disability and Rehabilitation Medicine (CONROD), The University of Queensland, Level 3, Mayne Medical School, Herston Road, Brisbane, QLD 4006, Australia
    • Corresponding Author InformationCorresponding author. Tel.: +011-61-7-3365-5558; fax: +011-61-7-3346-4603.
    • ,
  • Mary J. Bell

      Affiliations

    • Rheumatology and Clinical Epidemiology, Sunnybrook & Women's College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    • ,
  • Charlie H. Goldsmith

      Affiliations

    • Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    • ,
  • Shelley Lee

      Affiliations

    • i3 Innovus, Burlington, Ontario, Canada
    • ,
  • Michael Maschio

      Affiliations

    • i3 Innovus, Burlington, Ontario, Canada
    • ,
  • Jean-Pierre Raynauld

      Affiliations

    • Department of Medicine, University of Montreal, Montreal Institute of Rheumatology, Montreal, PQ, Canada
    • ,
  • George W. Torrance

      Affiliations

    • Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    • i3 Innovus, Burlington, Ontario, Canada
    • ,
  • Peter Tugwell

      Affiliations

    • Department of Medicine, Faculty of Medicine, Ottawa Hospital, General Campus, Ottawa, Ontario, Canada
    • Centre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada

,Accepted 4 August 2009.

References 

  1. Bellamy N, Wilson C, for the REFLECT Study Group . International estimation of Minimum Clinically Important Improvement (MCII75): the Reflect Study. Intern Med J. 2007;37(Suppl 2):A36
  2. Bellamy N, Wilson C, for the REFLECT Study Group . International estimation of Patient Acceptable Symptom Severity (PASS75): the Reflect Study. Intern Med J. 2007;37(Suppl 2):A36
  3. Pham T, van der Heijde D, Altman RD, Anderson JJ, Bellamy N, Hochberg M, et al. OMERACT-OARSI initiative: osteoarthritis research society international set of responder criteria for osteoarthritis clinical trials revisited. Osteoarthritis Cartilage. 2004;12:389–399
  4. Tubach F, Ravaud P, Baron G, Falissard B, Logeart I, Bellamy N, et al. Evaluation of clinically relevant changes in patient-reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement. Ann Rheum Dis. 2005;64(1):29–33
  5. Ehrich EW, Davies GM, Watson DJ, Bolognese JA, Seidenberg BC, Bellamy N. Minimal perceptible clinical improvement with the Western Ontario and McMaster Universities osteoarthritis index questionnaire and global assessments in patients with osteoarthritis. J Rheumatol. 2000;27:2635–2641
  6. Bellamy N, Bell M, Goldsmith CH, Pericak D, Walker V, Raynauld J-P, et al. Evaluation of WOMAC 20, 50, 70 response criteria in patients treated with hylan G-F 20 for knee osteoarthritis. Ann Rheum Dis. 2005;64:881–885
  7. Tubach F, Baron G, Ravaud P, Fallissard B, Logeart I, Bombardier C, et al. Evaluation of clinically relevant changes and states in symptomatic variables in osteoarthritis. Arthritis Rheum. 2003;48(Suppl):S292
  8. Tubach F, Ravaud P, Baron G, Falissard B, Logeart I, Bellamy N, et al. Evaluation of clinically relevant states in patient-reported outcomes in knee and hip osteoarthritis: the patient acceptable symptom state. Ann Rheum Dis. 2005;64(1):34–37
  9. Bellamy N, Bell MJ, Pericak D, Goldsmith CH, Torrance GW, Raynauld J-P, et al. BLISS index for analysing knee osteoarthritis trials data. J Clin Epidemiol. 2007;60(2):124–132
  10. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt L. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15:1833–1840
  11. Bellamy N, Krupa D, Markind JE, Reicin AS, Malmstrom K. Prevalence of patients with low intensity pain symptom severity states during treatment with rofecoxib and ibuprofen for osteoarthritis. OARSI Congress 2004. Osteoarthritis Cartilage. 2004;12(Suppl B):S69
  12. Bellamy N, Campbell J, Haraoui B, Gerecz-Simon E, Buchbinder R, Hobby K, et al. Clinimetric properties of the AUSCAN osteoarthritis hand index: an evaluation of reliability, validity and responsiveness. Osteoarthritis Cartilage. 2002;10:863–869
  13. Kvien TK, Zhang YZ, Nicols M, Dougados M, Podrebarac TA, Bellamy N. Response and state-attainment criteria in hand OA: analyses from a placebo-controlled clinical trial of CRX-102, a novel synergistic combination therapy. Ann Rheum Dis. 2007;66(Suppl II):501
  14. Raynauld JP, Torrance GW, Band PA, Goldsmith CH, Tugwell P, Walker V, et al. A prospective, randomized, pragmatic, health outcomes trial evaluating the incorporation of hylan G-F 20 into the treatment paradigm for patients with knee osteoarthritis (part 1 of 2): clinical results. Osteoarthritis Cartilage. 2002;10:506–517
  15. Hochberg MC, Altman RD, Brandt KD, Clark BM, Dieppe PA, Griffin MR, et al. Guidelines for the medical management of osteoarthritis, part II. Osteoarthritis of the knee. Arthritis Rheum. 1995;38:1541–1546
  16. Torrance G, Raynauld JP, Walker V, Goldsmith CH, Bellamy N, Band P, et al. A prospective randomized health outcomes trial evaluating the incorporation of hylan GF-20 into the treatment paradigm for patients with knee osteoarthritis (part 2 of 2): economic results. Osteoarthritis Cartilage. 2002;10:518–527
  17. Scale D, Wobig M, Wolpert W. Viscosupplementation of osteoarthritic knees with hylan: a treatment schedule study. Curr Ther Res. 1994;55:220–232
  18. Wobig M, Bach G, Beks P, Dickhut A, Runzheimer J, Schwieger G, et al. The role of elastoviscosity in the efficacy of viscosupplementation for osteoarthritis of the knee: a comparison of hylan G-F 20 and a lower-molecular-weight hyaluronan. Clin Ther. 1999;21:1549–1562
  19. Little RJA, Rubin DB. Statistical analysis with missing data. 2nd ed. Hoboken, NJ: John Wiley & Sons, Inc.; 2002;
  20. Bellamy N, Wilson C, Hendrikz JK. Community-based normative values for disability derived from WOMAC and AUSCAN NRS 3.1 indices. Ann Rheum Dis. 2007;66(Suppl II):491
  21. Bellamy N, Wilson C, Hendrikz J. Community-based normative values for pain, stiffness and disability derived from the WOMAC NRS 3.1 index. EULAR 2008. Ann Rheum Dis. 2008;67(Suppl II):228

PII: S0895-4356(09)00224-8

doi: 10.1016/j.jclinepi.2009.07.011

Journal of Clinical Epidemiology
Volume 63, Issue 5 , Pages 566-574 , May 2010

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