Journal of Clinical Epidemiology
Volume 63, Issue 4 , Pages 353-354, April 2010

Interim analysis in randomized trials: DAMOCLES' sword?

  • Marc G.H. Besselink

      Affiliations

    • Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Yolanda van der Graaf

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Hein G. Gooszen

      Affiliations

    • Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    • Corresponding Author InformationCorresponding author. Department of Surgery, HP G04.228, PO Box 85500, 3508 GA Utrecht, The Netherlands. Tel.: 0031-88-7555555; Fax: 0031-30-2541944.

Accepted 14 July 2009. published online 04 December 2009.

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PII: S0895-4356(09)00209-1

doi:10.1016/j.jclinepi.2009.07.004

Journal of Clinical Epidemiology
Volume 63, Issue 4 , Pages 353-354, April 2010