Journal of Clinical Epidemiology
Volume 63, Issue 3 , Pages 238-245 , March 2010

Meta-analysis of well-designed nonrandomized comparative studies of surgical procedures is as good as randomized controlled trials

  • Ned S. Abraham

      Affiliations

    • Faculty of Medicine, The Coffs Harbour Health Campus, The University of New South Wales, Coffs Harbour, NSW, Australia
    • The Surgical Outcomes Research Centre (SOuRCe), Sydney South West Area Health Service, The University of Sydney, Sydney, Australia
    • Corresponding Author InformationCorresponding author. Coffs Harbour Campus, Faculty of Medicine, University of New South Wales, POB 2244, Coffs Harbour, NSW 2450, Australia. Tel: +612-6652-0411; fax: +612-6652-0400.
    • ,
  • Christopher J. Byrne

      Affiliations

    • The Surgical Outcomes Research Centre (SOuRCe), Sydney South West Area Health Service, The University of Sydney, Sydney, Australia
    • Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia
    • ,
  • Jane M. Young

      Affiliations

    • The Surgical Outcomes Research Centre (SOuRCe), Sydney South West Area Health Service, The University of Sydney, Sydney, Australia
    • Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia
    • ,
  • Michael J. Solomon

      Affiliations

    • The Surgical Outcomes Research Centre (SOuRCe), Sydney South West Area Health Service, The University of Sydney, Sydney, Australia
    • Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia

,Accepted 17 April 2009.

  • Image Result

    Meta-analysis of nonrandomized comparative studies of laparoscopic vs. open resection for colorectal cancer (dichotomous variables). Odds ratio and 95% confidence intervals are represented by [--|--].

    Meta-analysis of nonrandomized comparative studies of laparoscopic vs. open resection for colorectal cancer (dichotomous variables). Odds ratio and 95% confidence intervals are represented by [--|--].

  • Image Result
    Effect of study design and conduct issues on measured odds ratio (OR) of morbidity rates in meta-analysis of 35 nonrandomized comparative studies of laparoscopic vs. open resection for colorectal canc

    Effect of study design and conduct issues on measured odds ratio (OR) of morbidity rates in meta-analysis of 35 nonrandomized comparative studies of laparoscopic vs. open resection for colorectal cancer. OR and 95% confidence intervals are represented by [--|--].

PII: S0895-4356(09)00127-9

doi: 10.1016/j.jclinepi.2009.04.005

Journal of Clinical Epidemiology
Volume 63, Issue 3 , Pages 238-245 , March 2010

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