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Volume 62, Issue 12, Pages 1323-1331 (December 2009)


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Estimating a preference-based index from the Japanese SF-36

John E. BrazieraCorresponding Author Informationemail address, Shunichi Fukuharab, Jennifer Robertsc, Samer Kharroubid, Yosuke Yamamotob, Shunya Ikedae, Jim Dohertyf, Kiyoshi Kurokawag

Accepted 27 January 2009. published online 17 July 2009.

Abstract 

Objective

The main objective of the study was to estimate a preference-based Short Form (SF)-6D index from the SF-36 for Japan and compare it with the UK results.

Study Design and Setting

The SF-6D was translated into Japanese. Two hundred and forty-nine health states defined by this version of the SF-6D were then valued by a representative sample of 600 members of the Japanese general population using standard gamble (SG). These health-state values were modeled using classical parametric random-effect methods with individual-level data and ordinary least squares (OLS) on mean health-state values, together with a new nonparametric approach using Bayesian methods of estimation.

Results

All parametric models estimated on Japanese data were found to perform less well than their UK counterparts in terms of poorer goodness of fit, more inconsistencies, larger prediction errors and bias, and evidence of systematic bias in the predictions. Nonparametric models produce a substantial improvement in out-of-sample predictions. The physical, role, and social dimensions have relatively larger decrements than pain and mental health compared with those in the United Kingdom.

Conclusion

The differences between Japanese and UK valuations of the SF-6D make it important to use the Japanese valuation data set estimated using the nonparametric Bayesian technique presented in this article.

a Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Yorkshire, UK

b Department of Epidemiology and Healthcare Research, Graduate School of Medicine, Kyoto University, Kyoto, Japan

c Department of Economics, University of Sheffield, University of Sheffield, Yorkshire, UK

d Department of Mathematics, University of York, Heslington, York, UK

e Department of Pharmaceutical Sciences, School of Pharmacy, International University and Health Welfare, Otawara, Tochigi, Japan

f GlaxoSmithKline, Research Triangle Park, NC, USA

g National Graduate Institute for Policy Studies, Tokyo, Japan

Corresponding Author InformationCorresponding author. Health Economics and Decision Science, The University of Sheffield, Regent Court, 30 Regent Street, Sheffield, Yorkshire S10 2FD, United Kingdom. Tel.: +44-114-2724095.

PII: S0895-4356(09)00062-6

doi:10.1016/j.jclinepi.2009.01.022


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