Journal of Clinical Epidemiology
Volume 62, Issue 5 , Pages 464-475 , May 2009

A pragmatic–explanatory continuum indicator summary (PRECIS): a tool to help trial designers

  • Kevin E. Thorpe

      Affiliations

    • Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada M5T 3M7
    • Corresponding Author InformationCorresponding author. Tel.: +416 864 5776; fax: +416 864 6057.
  • ,
  • Merrick Zwarenstein

      Affiliations

    • Centre for Health Services Sciences, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre; Institute for Clinical Evaluative Sciences; Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada
  • ,
  • Andrew D. Oxman

      Affiliations

    • Preventive and International Health Care Unit, Norwegian Knowledge Centre for the Health Services, Oslo, Norway
  • ,
  • Shaun Treweek

      Affiliations

    • Division of Clinical & Population Sciences and Education, University of Dundee, Dundee, UK; Norwegian Knowledge Centre for the Health Services, Oslo, Norway
  • ,
  • Curt D. Furberg

      Affiliations

    • Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA
  • ,
  • Douglas G. Altman

      Affiliations

    • Centre for Statistics in Medicine, University of Oxford, Oxford, UK
  • ,
  • Sean Tunis

      Affiliations

    • Center for Medical Technology Policy, Baltimore, MD, USA
  • ,
  • Eduardo Bergel

      Affiliations

    • UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Department of Reproductive Health and Research, World Health Organization, Geneva, Switzerland
  • ,
  • Ian Harvey

      Affiliations

    • Faculty of Health, University of East Anglia, Norwich, UK
  • ,
  • David J. Magid

      Affiliations

    • Institute for Health Research, Kaiser Permanente Colorado; Departments of Preventive Medicine and Biometrics and Emergency Medicine, University of Colorado Health Sciences Center, Denver, CO, USA
  • ,
  • Kalipso Chalkidou

      Affiliations

    • National Institute for Health and Clinical Excellence, London, UK

,Accepted 13 December 2008.

  • Image Result

    The blank pragmatic–explanatory continuum indicator summary (PRECIS) “wheel.”

    The blank pragmatic–explanatory continuum indicator summary (PRECIS) “wheel.”

  • Image Result

    (a) PRECIS summary of a randomized controlled trial of self-supervised and directly observed treatment of tuberculosis (DOT) [9]. (b) PRECIS summary of the North American Symptomatic Carotid Endartere

    (a) PRECIS summary of a randomized controlled trial of self-supervised and directly observed treatment of tuberculosis (DOT) [9]. (b) PRECIS summary of the North American Symptomatic Carotid Endarterectomy Trial (NASCET) of carotid endarterectomy for symptomatic patients with high-grade carotid stenosis [10]. (c) PRECIS summary of a randomized trial of low-dose aspirin for the prevention and treatment of pre-eclampsia (Collaborative Low-dose Aspirin Study in Pregnancy [CLASP]) [11]. (d) PRECIS summary of a randomized trial of low-dose aspirin for the prevention of pre-eclampsia in women at high risk [12].

 This article is being published in both the Canadian Medical Association Journal and the Journal of Clinical Epidemiology.

PII: S0895-4356(09)00048-1

doi: 10.1016/j.jclinepi.2008.12.011

Journal of Clinical Epidemiology
Volume 62, Issue 5 , Pages 464-475 , May 2009