Journal of Clinical Epidemiology
Volume 62, Issue 1 , Pages 47-53.e3 , January 2009

Publication bias was not a good reason to discourage trials with low power

  • George F. Borm

      Affiliations

    • Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, the Netherlands
    • Corresponding Author InformationCorresponding author.Radboud University Nijmegen Medical Centre, Department of Epidemiology and Biostatistics 133, P.O. Box 9101, NL-6500 HB Nijmegen, The Netherlands. Tel.: +31-243617667; fax: +31-243613505.
  • ,
  • Martin den Heijer

      Affiliations

    • Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, the Netherlands
    • Department of Endocrinology, Radboud University Nijmegen Medical Centre, the Netherlands
  • ,
  • Gerhard A. Zielhuis

      Affiliations

    • Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, the Netherlands

,Accepted 29 February 2008.

  • Image Result

    FP error rates in single trials and series of trials with low heterogeneity (bold lines) or high heterogeneity (thin lines). SS and NS publication rates were 100%/100% (), 100%/90% (), 85%/70% () and

    FP error rates in single trials and series of trials with low heterogeneity (bold lines) or high heterogeneity (thin lines). SS and NS publication rates were 100%/100% (), 100%/90% (), 85%/70% () and 85%/60% ().

PII: S0895-4356(08)00087-5

doi: 10.1016/j.jclinepi.2008.02.017

Journal of Clinical Epidemiology
Volume 62, Issue 1 , Pages 47-53.e3 , January 2009