Journal of Clinical Epidemiology
Volume 61, Issue 10 , Pages 1067-1072, October 2008

The Brugada type 1 electrocardiographic pattern is common among Filipinos

  • Giselle Gervacio-Domingo

      Affiliations

    • University of Phillipines-Phillipines General Hospital, Section of Cardiology, Taft Ave, Manila, 1000 Philippines
    • Corresponding Author InformationCorresponding author. Tel./fax: +632-523-2010.
  • ,
  • Jessore Isidro

      Affiliations

    • University of Phillipines-Phillipines General Hospital, Section of Cardiology, Taft Ave, Manila, 1000 Philippines
  • ,
  • Jose Tirona

      Affiliations

    • Department of Internal Medicine, De La Salle University Medical Center, Congressional Road, Dasmarinas, 4114 Cavite
  • ,
  • Eden Gabriel

      Affiliations

    • Electrophysiology Section, Philippine Heart Center, East Avenue, Quezon city, Philippines
  • ,
  • Gladys David

      Affiliations

    • Department of Medicine, Cardinal Santos Medical Center, Wilson Street, Greenhills, San Juan, Metro Manila, Philippines
  • ,
  • Ma. Lourdes Amarillo

      Affiliations

    • Department of Clinical Epidemiology, University of the Philippines, Pedro Gil St., Manila, Philippines
  • ,
  • Dante Morales

      Affiliations

    • University of Phillipines-Phillipines General Hospital, Section of Cardiology, Taft Ave, Manila, 1000 Philippines
  • ,
  • Antonio Dans

      Affiliations

    • Department of Adult Medicine, University of the Philippines-Philippine General Hospital, Taft Avenue, Manila, 1000 Philippines

Accepted 17 November 2007. published online 19 June 2008.

Abstract 

Objective

To measure the prevalence of the Brugada type 1 ECG pattern in the general population in the Philippines.

Study Setting and Design

Sudden unexplained death syndrome is rare in the West but is common among Southeast Asians. Ventricular fibrillation is the terminal event. The Brugada type 1 electrocardiographic (ECG) pattern with J point and coved ST elevation in right precordial leads, is a marker for sudden unexplained death syndrome. Its prevalence in the general population is unknown. A cross-sectional nationwide survey was performed in the Philippines in 2003 using a stratified multistage sampling design covering all the regions and provinces in the country. ECGs were performed in all adults surveyed. The prevalences of the Brugada type 1 ECG pattern (coved type) and any type Brugada ECG pattern were determined.

Results

The Brugada type 1 (coved) ECG pattern in the general population in the Philippines was found in 0.2% (95% Confidence Interval [CI] 0.03%–0.36%) of the population. Among males the prevalence was 0.3% (±0.1). The prevalence of any type Brugada ECG was 2% (95% CI 1.5%–2.6%).

Conclusion

The Brugada ECG pattern is common among Filipinos. There is a need to determine the risk of sudden death among individuals with this marker in the general population.

Keywords: SUDS, Brugada ECG pattern, Asian SUDS, Sudden unexplained death, “Bangungut”, Sudden death

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PII: S0895-4356(07)00434-9

doi:10.1016/j.jclinepi.2007.11.009

Journal of Clinical Epidemiology
Volume 61, Issue 10 , Pages 1067-1072, October 2008