Journal of Clinical Epidemiology
Volume 59, Issue 11 , Pages 1125-1126 , November 2006

Why are so few randomized trials useful, and what can we do about it?

,Accepted 3 May 2006.

References 

  1. The Cochrane Central Register of Controlled Trials (CENTRAL). The Cochrane Library, Issue 1, 2006. Chichester: Wiley.
  2. McMaster PLUS (Premium Literature Ultra Service). Accessed March 31, 2006. Available at http://hiru.mcmaster.ca/plus/
  3. Tunis SR, Stryer DB, Clancy CM. Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy. JAMA. 2003;290:1624–1632
  4. Swartz D, Lellouch J. Explanatory and pragmatic attitudes in therapeutic trials. J Chronic Dis. 1967;20:637–648
  5. Treweek S, McCormack K, Abalos E, Campbell M, Ramsay C, Zwarenstein M on behalf of the Practihc Collaboration. The Trial Protocol Tool: the PRACTIHC software tool that supported the writing of protocols for pragmatic randomized controlled trials. J Clin Epidemiol. 2006;59:1127–1133[this issue]
  6. Pragmatic Trials in Health Care Systems (PRACTIHC): an international network to facilitate information for action on priority health problems. Funded by European Commission International Scientific Cooperation Projects, 5th Framework. International Collaboration with Developing Countries (INCO-DC). Accessed October 1, 2005. Available at http://www.practihc.org/.
  7. Gartlehner G, Hansen RA, Nissman D, Lohr KN, Carey TS. A simple and valid tool to distinguish efficacy from effectiveness studies. J Clin Epidemiol. 2006;59:1040–1048

PII: S0895-4356(06)00235-6

doi: 10.1016/j.jclinepi.2006.05.010

Journal of Clinical Epidemiology
Volume 59, Issue 11 , Pages 1125-1126 , November 2006