Clinical heterogeneity was a common problem in Cochrane reviews of physiotherapy and occupational therapy

References 

1. WHO . International classification of functioning, disability and health (ICF). In: Geneva, Switzerland: World Health Organization; 2001;
2. Driessen MJ, Dekker J, Van der Zee J, Lankhorst GJ. Diagnostic findings and treatment goals in occupational therapy in hospital based care in the Netherlands. Occup Ther Int. 1996;3:142–156
   • CrossRef
3. Van Baar M, Dekker J, Bosveld W. A survey of physical therapy goals and interventions for patients with back and knee pain. Phys Ther. 1998;78:33–42
   • MEDLINE
4. Kane RL. Looking for physical therapy outcomes. Phys Ther. 1994;74:425–429
   • MEDLINE
5. Edwards DF. The effect of occupational therapy on function and well-being. In:  Christiansen C,  Baum C editor. Occupational therapy enabling function and well-being. 2nd ed. New York: Slack Incorporated; 1997;p. 556–574
6. Assendelft W, Morton S, Yu EI, Suttorp M, Shekelle P. Spinal manipulative therapy for low back pain. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
7. Bonaiuti D, Shea B, Iovine R, et al. Exercise for preventing and treating osteoporosis in postmenopausal women. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
8. Bradley J, Moran F, Greenstone M. Physical training for bronchiectasis. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
9. Bradley J, Moran F. Physical training for cystic fibrosis. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
10. Brosseau L, Casimiro L, Milne S, et al. Deep transverse friction massage for treating tendinitis. In: The Cochrane Library, Issue 4. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
11. Brosseau L, MacLeay L, Robinson V, Wells G, Tugwell P. Intensity of exercise for the treatment of osteoarthritis. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
12. Busch A, Schachter CL, Peloso PM, Bombardier C. Exercise for treating fibromyalgia syndrome. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
13. Campbell K, Waters E, O'Meara S, Kelly S, Summerbell C. Interventions for preventing obesity in children. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
14. Dagfinrud H, Hagen K. Physiotherapy interventions for ankylosing spondylitis. In: The Cochrane Library, Issue 4. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
15. Deane KH, Jones D, Playford ED, Ben Shlomo Y, Clarke CE. Physiotherapy for patients with Parkinson's Disease: a comparison of techniques. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
16. Deane KH, Ellis-Hill C, Playford ED, Ben Shlomo Y, Clarke CE. Occupational therapy for patients with Parkinson's disease. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
17. Deane KH, Whurr R, Clarke CE, Playford ED, Ben Shlomo Y. Non-pharmacological therapies for dysphagia in Parkinson's disease. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
18. Deane KH, Jones D, Ellis-Hill C, Clarke CE, Playford ED, Ben Shlomo Y. A comparison of physiotherapy techniques for patients with Parkinson's disease. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
19. Fransen M, McConnell S, Bell M. Exercise for osteoarthritis of the hip or knee. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
20. French J, Bilton D, Campbell F. Nurse specialist care for bronchiectasis. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
21. Furlan AD, Brosseau L, Imamura M, Irvin E. Massage for low back pain. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
22. Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH. Interventions for preventing falls in elderly people. In: The Cochrane Library, Issue 4. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
23. Glasscoe CA, Quittner AL. Psychological interventions for cystic fibrosis. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
24. Gross AR, Hoving JL, Haines TA, et al. Manipulation and mobilisation for mechanical neck disorders. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
25. Guzman J, Esmail R, Karjalainen K, Malmivaara A, Irvin E, Bombardier C. Multidisciplinary bio-psycho-social rehabilitation for chronic low back pain. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
26. Handoll HH, Madhok R, Howe TE. Rehabilitation for distal radial fractures in adults. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
27. Handoll HH, Parker MJ, Sherrington C. Mobilisation strategies after hip fracture surgery in adults. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
28. Hay-Smith EJ, Bo Berghmans LC, Hendriks HJ, de Bie RA, van Waalwijk van Doorn ES. Pelvic floor muscle training for urinary incontinence in women. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2001;
29. Hay-Smith J, Herbison P, Morkved S. Physical therapies for prevention of urinary and faecal incontinence in adults. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
30. Hayes RL, McGrath JJ. Cognitive rehabilitation for people with schizophrenia and related conditions. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
31. Heintjes E, Berger MY, Bierma-Zeinstra SM, Bernsen RM, Verhaar JA, Koes BW. Exercise therapy for patellofemoral pain syndrome. In: The Cochrane Library, Issue 4. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
32. Holloway E, Ram F. Breathing exercises for asthma. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
33. Hondras MA, Linde K, Jones AP. Manual therapy for asthma. In: The Cochrane Library, Issue 4. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
34. Lacasse Y, Brosseau L, Milne S, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
35. Latham N, Anderson C, Bennett D, Stretton C. Progressive resistance strength training for physical disability in older people. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
36. Leng GC, Fowler B, Ernst E. Exercise for intermittent claudication. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
37. McDonald S, Hetrick S, Green S. Pre-operative education for hip or knee replacement. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
38. Moseley AM, Stark A, Cameron ID, Pollock A. Treadmill training and body weight support for walking after stroke. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
39. Nixon S, O'Brien K, Glazier RH, Tynan AM. Aerobic exercise interventions for adults living with HIV/AIDS. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
40. Ostelo RW, de Vet HC, Waddell G, Kerckhoffs MR, Leffers P, van Tulder MW. Rehabilitation after lumbar disc surgery. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
41. Outpatient Service Trialists . Therapy-based rehabilitation services for stroke patients at home. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
42. Pollock A, Baer G, Pomeroy V, Langhorne P. Physiotherapy treatment approaches for the recovery of postural control and lower limb function following stroke. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
43. Ram FS, Robinson SM, Black PN. Physical training for asthma. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
44. Wallace SARB, Williams K, Palmer M. Bladder training for urinary incontinence in adults. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
45. Saunders D, Greig C, Young A, Mead G. Physical fitness training for stroke patients. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
46. Schonstein E, Kenny DT, Keating J, Koes BW. Work conditioning, work hardening and functional restoration for workers with back and neck pain. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
47. Steultjens E, Dekker J, Bouter L, Schaardenburg D, Kuyk M, Ende C. Occupational therapy for rheumatoid arthritis. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
48. Steultjens EM, Dekker J, Bouter LM, Cardol M, Van de Nes JC, Van den Ende CH. Occupational therapy for multiple sclerosis. In: The Cochrane Library, Issue 3. Chichesters, UK: John Wiley & Son, Ltd.; 2003;
49. Thomson LC, Handoll HH, Cunningham A, Shaw PC. Physiotherapist-led programmes and interventions for rehabilitation of anterior cruciate ligament, medial collateral ligament and meniscal injuries of the knee in adults. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
50. Van den Ende CH, Vliet Vlieland TP, Munneke M, Hazes JM. Dynamic exercise therapy for rheumatoid arthritis. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
51. van der Schans C, Prasad A, Main E. Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
52. Van Tulder M, Malmivaara A, Esmail R, Koes B. Exercise therapy for low back pain. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
53. Van Tulder M, Esmail R, Bombardier C, Koes BW. Back schools for non-specific low back pain. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
54. Verhagen A, Bierma-Zeinstra S, Feleus A, et al. Ergonomic and physiotherapeutic interventions for treating upper extremity work related disorders in adults. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2004;
55. Verhagen AP, de Vet HC, de Bie RA, Kessels AG, Boers M, Knipschild PG. Balneotherapy for rheumatoid arthritis and osteoarthritis. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
56. Vickers A, Ohlsson A, Lacy JB, Horsley A. Massage for promoting growth and development of preterm and/or low birth-weight infants. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2000;
57. Young G, Jewell D. Interventions for preventing and treating pelvic and back pain in pregnancy. In: The Cochrane Library, Issue 1. Chichesters, UK: John Wiley & Son, Ltd.; 2002;
58. Tugwell P, Brooks P, Wells G, et al. Musculoskeletal group. In: The Cochrane Library, Issue 1. Chichester, UK: John Wiley & Sons, Ltd; 2004;
59. Smidt N, Assendelft WJJ, Van der Windt DAWM, et al. Corticosteroid injections for lateral epicondylitis: a systematic review. Pain. 2002;96:23–40
    • Abstract
    • Full Text
    • Full-Text PDF (225 KB)
    • CrossRef
60. Alderson P, Green S, Higgins JPT, Eds. Cochrane reviewers' handbook 4.2.2. [updated December 2003]. http://www.cochrane.org/resources/handbook/hbook.htm (accessed 31st August 2004). 2004.
61. Schmid CH, Stark PC, Berlin JA, Landais P, Lau P. Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors. J Clin Epidemiol. 2004;57:683–697
    • Abstract
    • Full Text
    • Full-Text PDF (418 KB)
    • CrossRef
62. Hofhuis H, De Boer M, Plas M, Van den Ende, CH. Enkelvoudige extramurale ergotherapie: stand van zaken 2002 (Occupational therapy home based care in the Netherlands: the state of the art in 2002). Utrecht, The Netherlands: Institute for Health Services Research (NIVEL); 2003.
63. Wimmers R, Swinkels I, De Konink M, De Bakker D, Van den Ende CH. Jaarboek LiPZ, beroepsgroep Fysiotherapie. (Yearly Report LiPZ, the profession physical therapy). Utrecht, The Netherlands: NIVEL; 2003.
64. Robertson S, Colborn A. Can we improve outcomes research by expanding research methods?. Am J Occup Ther. 2000;55:541–543
65. Unsworth C. Measuring the outcome of occupational therapy: tools and resources. Aust Occup Ther J. 2000;47:147–158
    • CrossRef
66. Söderback I. Effectiveness of rehabilitation. Crit Rev Phys Rehab Med. 1995;7:275–286
67. Ferreira PH, Ferreira ML, Maher CG, Refshauge K, Herbert RD, Latimer J. Effect of applying different levels of evidence criteria on conclusions of Cochrane reviews of interventions for low back pain. J Clin Epidemiol. 2002;55:1126–1129
    • Abstract
    • Full Text
    • Full-Text PDF (68 KB)
    • CrossRef
68. Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research evidence. N Eng J Med. 2000;342:1887–1892
69. Haynes RB. What kind of evidence is it that evidence based medicine advocates want health care providers and consumers to pay attention to?. BMC Health Serv Res. 2002;2:3
    • MEDLINE
    • CrossRef
70. McKee M, Britton A, Black N, McPherson K, Sanderson C, Bain C. Interpreting the evidence: choosing between randomised and non randomised studies. BMJ. 1999;319:312–315
    • MEDLINE
    • CrossRef
71. Britton A, McPherson K, McKee M, Sanderson C, Black N, Bain C. Choosing between randomised and non-randomised studies: a systematic review. Health Technol Assess. 1998;2:1–24
    • MEDLINE
72. Benson K, Harthz AJ. A comparison of observational studies and randomized controlled trials. N Eng J Med. 2000;342:1878–1886
73. Pocock SJ, Elbourne DR. Randomized trials or observational tribulations? (editorial). N Eng J Med. 2000;342:1907–1909
74. Shapiro S. Meta-analysis/Shmeta-analysis. Am J Epidemiol. 1994;140:771–778
    • MEDLINE
75. Egger M, Schneider M, Smith GD. Spurious precision? Meta-analysis of observational studies. BMJ. 1998;316:140–144
    • MEDLINE
    • CrossRef
76. Van Tulder M, Cherkin DC, Berman B, Lao L, Koes BW. Acupuncture for low-back pain. In: The Cochrane Library, Issue 2. Chichesters, UK: John Wiley & Son, Ltd.; 2004;