Journal of Clinical Epidemiology
Volume 59, Issue 3 , Pages 308-314 , March 2006

A new method for assessing drug causation provided agreement with experts' judgment

  • Yannick Arimone

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • Université Victor Segalen Bordeaux 2, Département de Pharmacologie, Case 36-146, Rue Léo Saignat, 33076 Bordeaux Cedex, France
    • ,
  • Bernard Bégaud

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • Université Victor Segalen Bordeaux 2, Département de Pharmacologie, Case 36-146, Rue Léo Saignat, 33076 Bordeaux Cedex, France
    • Corresponding Author InformationCorresponding author. Tel.: +33-557-571561; fax: +33-557-574660.
    • ,
  • Ghada Miremont-Salamé

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • CHU de Bordeaux, Hôpital Pellegrin, Centre de Pharmacovigilance, 33076 Bordeaux Cedex, France
    • ,
  • Annie Fourrier-Réglat

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • Université Victor Segalen Bordeaux 2, Département de Pharmacologie, Case 36-146, Rue Léo Saignat, 33076 Bordeaux Cedex, France
    • ,
  • Mathieu Molimard

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • Université Victor Segalen Bordeaux 2, Département de Pharmacologie, Case 36-146, Rue Léo Saignat, 33076 Bordeaux Cedex, France
    • ,
  • Nicholas Moore

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • Université Victor Segalen Bordeaux 2, Département de Pharmacologie, Case 36-146, Rue Léo Saignat, 33076 Bordeaux Cedex, France
    • ,
  • Françoise Haramburu

      Affiliations

    • INSERM U657, 33076 Bordeaux Cedex, France
    • CHU de Bordeaux, Hôpital Pellegrin, Centre de Pharmacovigilance, 33076 Bordeaux Cedex, France

,Accepted 1 August 2005.

  • Image Result

    Distribution of probabilities of drug causation in gold standard; 84% of probabilities were greater than .5.

    Distribution of probabilities of drug causation in gold standard; 84% of probabilities were greater than .5.

  • Image Result

    Using the logistic function to obtain the probability of drug causation from the sum of scores.

    Using the logistic function to obtain the probability of drug causation from the sum of scores.

PII: S0895-4356(05)00333-1

doi: 10.1016/j.jclinepi.2005.08.012

Journal of Clinical Epidemiology
Volume 59, Issue 3 , Pages 308-314 , March 2006

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