Journal of Clinical Epidemiology
Volume 58, Issue 8 , Pages 785-790 , August 2005

Powering our way to the elusive side effect: A composite outcome ‘basket’ of predefined designated endpoints in each organ system should be included in all controlled trials

  • Peter Tugwell

      Affiliations

    • Institute of Population Health, University of Ottawa, 1 Stewart Street, Room 312, Ottawa, Ontario K1N 6N5, Canada
    • Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    • Corresponding Author InformationCorresponding author. Tel.: 613-562-5800 ext. 1945; fax: 613-562-5659.
  • ,
  • Maria G. Judd

      Affiliations

    • Institute of Population Health, University of Ottawa, 1 Stewart Street, Room 312, Ottawa, Ontario K1N 6N5, Canada
  • ,
  • Jim F. Fries

      Affiliations

    • Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA
  • ,
  • Gurkirpal Singh

      Affiliations

    • Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA
  • ,
  • George A. Wells

      Affiliations

    • Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada

,Accepted 30 November 2004.

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PII: S0895-4356(05)00109-5

doi: 10.1016/j.jclinepi.2004.11.028

Journal of Clinical Epidemiology
Volume 58, Issue 8 , Pages 785-790 , August 2005