Journal of Clinical Epidemiology
Volume 57, Issue 11 , Pages 1214-1217 , November 2004

Two measures of insulin sensitivity provided similar information in a U.S. population

  • Dawn M. Bravata

      Affiliations

    • Clinical Epidemiology Unit, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Medicine Service, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room IE-61 SHM, New Haven, CT 06520-8025, USA
    • Corresponding Author InformationCorresponding author. Tel.: 203-932-5711 ext. 4240; fax: 203-785-3461.
    • ,
  • Carolyn K. Wells

      Affiliations

    • Clinical Epidemiology Unit, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room IE-61 SHM, New Haven, CT 06520-8025, USA
    • ,
  • John Concato

      Affiliations

    • Clinical Epidemiology Unit, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Medicine Service, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room IE-61 SHM, New Haven, CT 06520-8025, USA
    • ,
  • Walter N. Kernan

      Affiliations

    • Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room IE-61 SHM, New Haven, CT 06520-8025, USA
    • ,
  • Lawrence M. Brass

      Affiliations

    • Neurology Service, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Department of Neurology, Yale University School of Medicine, New Haven, CT, USA
    • ,
  • Barbara I. Gulanski

      Affiliations

    • Medicine Service, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA
    • Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, Room IE-61 SHM, New Haven, CT 06520-8025, USA

,Accepted 3 May 2004.

References 

  1. Despres J-P, LaMarche B, Mauriege P, Cantin B, Dagenais GR, Moorjani S, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med. 1996;334:952–957
  2. Feskens E, Kromhout D. Hyperinsulinemia, risk factors, and coronary heart disease: the Zutphen Elderly Study. Arterioscler Thromb. 1994;14:1641–1647
  3. Folsom A, Rasmussen M, Chambless L, Howard G, Cooper LS, Schmidt MI, et al. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. Diabetes Care. 1999;22:1077–1083
  4. Kuusisto J, Mykkanen L, Pyorala K, Laakso M. Hyperinsulinemic microalbuminuria: a new risk indicator for coronary heart disease. Circulation. 1995;91:831–837
  5. Lakka H-M, Lakka TA, Tuomilehto J, Sivenius J, Salonen JT. Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Arch Intern Med. 2000;160:1160–1168
  6. Shinozaki K, Naritomi H, Shimizu T, Suzuki M, Ikebuchi M, Sawada T, et al. Role of insulin resistance associated with compensatory hyperinsulinemia in ischemic stroke. Stroke. 1996;27:37–43
  7. Perry IJ, Wannamethee SG, Whincup PH, Shaper AG, Walker MK, Alberti KG. Serum insulin and incident coronary heart disease in middle-aged British men. Am J Epidemiol. 1996;144:224–234
  8. Pyorala M, Miettinen H, Laakso M, Pyorala K. Hyperinsulinemia and the risk of stroke in healthy middle-aged men: the 22 year follow-up results of the Helsinki Policemen Study. Stroke. 1998;29:1860–1866
  9. Wannamethee SG, Perry IJ, Shaper AG. Nonfasting serum glucose and insulin concentrations and the risk of stroke. Stroke. 1999;30:1780–1786
  10. DeFronzo R, Tobin J, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979;237:E214–E223
  11. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412–419
  12. Hanson RL, Pratley RE, Bogardus C, Narayan KM, Roumain JM, Imperatore G, et al. Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies. Am J Epidemiol. 2000;151:190–198
  13. U.S.National Center for Health Statistics . Third National Health and Nutrition Examination Survey (NHANES III), 1988–94 on CD-ROM NHANES III Laboratory Data File. Public Use Data File Documentation Number 76200. Hyattsville, MD: U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics; 1997;
  14. Harris MI, Flegal KM, Cowie CC, Eberhardt MS, Goldstein DE, Little RR, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994. Diabetes Care. 1998;21:518–524
  15. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus . Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2003;26(Suppl 1):S5–S20
  16. Feinstein AR. Principles of medical statistics. Boca Raton, FL: Chapman & Hall/CRC Press; 2002;
  17. Matsuda M, DeFronzo R. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22:1462–1470
  18. Wedick N, Mayer-Davis E, Wingard D, Addy C, Barrett-Connor E. Insulin resistance precedes weight loss in adults without diabetes: the Rancho Bernardo Study. [Erratum in: Am J Epidemiol 2002 Apr 15;155(8):781.] Am J Epidemiol. 2001;153:1199–1205
  19. Haffner S, Miettinen H, Stern M. The homeostasis model in the San Antonio Heart Study. Diabetes Care. 1997;20:1087–1092

PII: S0895-4356(04)00123-4

doi: 10.1016/j.jclinepi.2004.05.001

Journal of Clinical Epidemiology
Volume 57, Issue 11 , Pages 1214-1217 , November 2004

Article Tools