Journal of Clinical Epidemiology
Volume 56, Issue 7 , Pages 605-609 , July 2003

Who can best recruit to randomized trials? Randomized trial comparing surgeons and nurses recruiting patients to a trial of treatments for localized prostate cancer (the ProtecT study)

  • Jenny L. Donovan

      Affiliations

    • Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    • Division of Primary Health Care, University of Bristol, Cotham Hill, Bristol BS6 6JL, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44-(0)-117-928-7214; fax: +44-(0)-117-928-7325.
    • ,
  • Tim J. Peters

      Affiliations

    • Division of Primary Health Care, University of Bristol, Cotham Hill, Bristol BS6 6JL, UK
    • ,
  • Sian Noble

      Affiliations

    • Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    • ,
  • Philip Powell

      Affiliations

    • Department of Urology, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK
    • ,
  • David Gillatt

      Affiliations

    • Bristol Urologic Institute, Southmead Hospital, Southmead Road, Bristol BS10 5NB, UK
    • ,
  • Steven E. Oliver

      Affiliations

    • Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    • ,
  • J.Athene Lane

      Affiliations

    • Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    • ,
  • David E. Neal

      Affiliations

    • Department of Surgical Oncology, Oncology Centre, Addenbrook's Hospital, Hills Road, Cambridge CB2 2QQ, UK
    • ,
  • Freddie C. Hamdy

      Affiliations

    • Division of Surgical Sciences, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    • ,
  • for the ProtecT Study Group

References 

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  9. Folmar S, Oates-Williams F, Sharp P, Reboussin D, Smith J, Cheshire K, et al. Recruitment of participants for the Estrogen Replacement and Atherosclerosis (ERA) Trial: a comparison of costs, yields, and participant characteristics from community- and hospital-based recruitment strategies. Control Clin Trials. 2001;22:13–25
  10. Pressel S, Davis BR, Louis GT, Whelton P, Adrogue H, Egan D, et al. Participant recruitment in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): for the ALLHAT Research Group. Control Clin Trials. 2001;22:674–686
  11. Aaronson NK, Visser-Pol E, Leenhouts GH, Muller MJ, van der Schot AC, van Dam FS, et al. Telephone-based nursing intervention improves the effectiveness of the informed consent process in cancer clinical trials. J Clin Oncol. 1996;14:984–986
  12. Myles PS, Fletcher HE, Cairo S, Madder H, McRae R, Cooper J, et al. Randomized trial of informed consent and recruitment for clinical trials in the immediate preoperative period. Anesthesiology. 1999;91:969–978
  13. Jenkins VA, Fallowfield LJ, Souhami A, Sawtell M. How do doctors explain randomised clinical trials to their patients?. Eur J Cancer. 1999;35:1187–1193
  14. Hales G, Beveridge A, Smith D. The conflicting roles of clinicians versus investigators in HIV randomised clinical trials. Culture Health Sexual. 2001;3:67–79
  15. Baum M. New approach for recruitment into randomised controlled trials. Lancet (North Am Ed). 1993;341:812–813
  16. Sadler GR, Lantz JM, Fullerton JT, Dault Y. Nurses' unique roles in randomized clinical trials. J Prof Nurs. 1999;15:106–115
  17. Donovan JL, Mills N, Smith M, Brindle L, Jacoby A, Peters TJ, et al. Quality improvement report: improving design and conduct of randomised trials by embedding them in qualitative research: protect (prostate testing for cancer and treatment study). BMJ. 2002;325:766–770
  18. Mills N, Donovan JL, Smith M, Jacoby A, Neal DE, Hamdy FC. Patients' perceptions of equipoise are crucial to trial participation: a qualitative study of men in the ProtecT study. Control Clin Trials. 2003;24:272–282

☆ ProtecT Study Group: John Anderson, Miranda Benney, Lucy Brindle, Sally Burton, Daniel Dedman, Ingrid Emmerson, Cath Ferguson, Stephen Frankel, John Goepel, Louise Goodwin, John Graham, David Gunnell, Christine Hardy, Helen Harris, Barbara Hattrick, Peter Holding, David Jewell, Clare Kennedy, Sue Kilner, Peter Kirkbride, Hing Leung, Teresa Mewes, Jon Oxley, Ian Pedley, Andrew Robinson, Mary Robinson, Liz Salter, Mark Sidaway, Carol Torrington, Lyn Wilkinson, Andrea Wilson.

PII: S0895-4356(03)00083-0

doi: 10.1016/S0895-4356(03)00083-0

Journal of Clinical Epidemiology
Volume 56, Issue 7 , Pages 605-609 , July 2003

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